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Andrey Krasilnikov

address: 106 Althouse
location: Science, Eberly College
phone: 814-865-5050
e-mail: ask11@psu.edu
department: Biochemistry and Molecular Biology

Projects

Structural studies of RNA and RNA-protein complexes

We are interested in learning the atomic-resolution details of the spatial organization of highly structured RNA molecules and complexes of such molecules with RNA-binding proteins. Using X-ray crystallography we can determine the three-dimensional structure of the molecule to the finest details; using a combination of crystallographic and biochemical studies we can answer a very broad variety of fundamental questions, ranging from the mechanisms of substrate recognition and catalysis to the structural and functional roles of individual parts of the molecule or complex.

Website: http://bmb.psu.edu/directory/ask11
Number of undergraduates needed: undefined
Minimum qualifications: High motivation; commitment to spend at least 10 hours per week for at least 3 semesters; a decent science GPA.